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Synthesis of a repressible enzyme is inhibited by


A) repressor alone bound to operator.
B) substrate bound to repressor.
C) substrate bound to promoter.
D) corepressor and repressor binding to operator.

E) B) and D)
F) None of the above

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Which of the following is not true of conjugation?


A) involves direct contact between cells
B) transfers genes for drug resistance
C) transfers genes for enzymes and adherence molecules
D) transfers genes for a polysaccharide capsule
E) The donor retains a copy of the transferred genes.

F) B) and D)
G) A) and C)

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Each nucleotide is composed of


A) one phosphate, one nitrogenous base, one sugar.
B) one phosphate, one nitrogenous base, two sugars.
C) two phosphates, one nitrogenous base, one sugar.
D) two phosphates, one nitrogenous base, two sugars.
E) one phosphate, two nitrogenous bases, one sugar.

F) B) and E)
G) B) and D)

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Which of the following additions have been made to principles of the central dogma of biology?


A) DNA information cannot be converted into RNA information.
B) Protein information can be converted into DNA information.
C) RNA can be used to regulate gene function.
D) DNA codes for proteins.
E) All of these choices are correct.

F) All of the above
G) B) and E)

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A permanent, inheritable change in the genetic information is called a(n)


A) translation.
B) transcription.
C) mutation.
D) alteration.
E) regeneration.

F) None of the above
G) C) and D)

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Groups of three consecutive bases along the DNA of a gene have the code for one


A) protein.
B) nucleotide.
C) amino acid.
D) purine.

E) None of the above
F) C) and D)

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Introns have no detectable functions.

A) True
B) False

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Okazaki fragments are attached to the growing end of the lagging strand by


A) DNA ligase.
B) DNA polymerase.
C) DNA helicase.
D) DNA gyrase.
E) primase.

F) B) and D)
G) B) and E)

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A sequence of bases within a gene that will be transcribed, but removed from the transcript prior to translation is a/an


A) promoter.
B) operator.
C) operon.
D) exon.
E) intron.

F) C) and D)
G) B) and E)

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Gene regulation can involve a protein repressor that blocks _____ from initiating transcription.


A) DNA polymerase I
B) DNA polymerase III
C) RNA polymerase
D) mRNA
E) rRNA

F) A) and D)
G) C) and D)

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What type of mutation alters the base, but not the amino acid being coded for?


A) silent
B) back
C) point
D) nonsense
E) missense

F) D) and E)
G) B) and E)

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Hfr transfer involves all of the following except


A) gene integration into the bacterial chromosome.
B) plasmid gene transfer.
C) F factor is part of the F+ donor chromosome.
D) high frequency transfer.
E) a pilus connection between F+ and F- cells.

F) C) and D)
G) D) and E)

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Short interfering RNAs affect gene expression in eukaryotes by


A) blocking replication of certain genes.
B) blocking transcription of certain genes.
C) binding to mRNAs and preventing translation.
D) binding to ribosomes, preventing the two subunits from joining.

E) None of the above
F) B) and C)

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All of the following pertain to nitrogenous bases except


A) they form pairs by hydrogen bonding.
B) guanine pairs with uracil.
C) adenine pairs with thymine.
D) cytosine and thymine are pyrimidines.
E) they allow variation from one nucleotide to another which creates the encoded information.

F) A) and B)
G) A) and C)

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While studying the infection process and life cycle of a newly discovered virus, it was determined that the virus never entered the nucleus of the host cell.This virus may have any of the following genomes except


A) DNA.
B) double-stranded RNA.
C) single (+) strand RNA.
D) single (-) strand RNA.

E) All of the above
F) None of the above

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DNA photolyase, in the presence of visible light, can repair DNA damage due to ultraviolet radiation.

A) True
B) False

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The antiparallel arrangement within DNA molecules refers to


A) each base bonding at the 1'position of the sugar.
B) a purine always bonding to a pyrimidine.
C) one helix strand that runs from the 5'to 3'direction and the other strand runs from the 3'to 5'direction.
D) an original parent DNA strand and one newly synthesized DNA strand comprising a new DNA molecule.

E) B) and C)
F) None of the above

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A nucleosome is a linear chromosome wound around the


A) nuclear membrane.
B) rRNA.
C) mRNA.
D) histone.
E) nucleolus.

F) A) and E)
G) C) and D)

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The enzyme that can proofreads replicating DNA, detects incorrect bases, excises them, and correctly replaces them is


A) DNA ligase.
B) DNA polymerase.
C) DNA helicase.
D) DNA gyrase.
E) primase.

F) C) and D)
G) A) and D)

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Of the following list, which antibiotics affect protein synthesis?


A) penicillin
B) tetracycline
C) chloramphenicol
D) ciprofloxacin
E) Both tetracycline and chloramphenicol are correct.

F) B) and E)
G) B) and D)

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