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A negative-sense RNA virus


A) is ready for immediate translation.
B) must synthesize a negative RNA copy of its genome.
C) must synthesize a positive RNA copy of its genome.
D) is a special form of tRNA used by viruses.
E) always codes for RNA polymerase.

F) A) and B)
G) A) and C)

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A fully formed virus that can cause an infection in a host cell is called a virion.

A) True
B) False

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Viruses have all the following except


A) definite shape.
B) metabolism.
C) genes.
D) the ability to infect host cells.
E) ultramicroscopic size.

F) A) and B)
G) A) and C)

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New,nonenveloped virus release occurs by


A) lysis.
B) budding.
C) exocytosis.
D) both lysis and budding.
E) both budding and exocytosis.

F) A) and B)
G) A) and E)

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Host cells of viruses include


A) humans and other animals.
B) plants and fungi.
C) bacteria.
D) protozoa and algae.
E) All of the choices are correct.

F) B) and E)
G) D) and E)

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Mrs. Hammond is a 79-year-old woman who has been a resident on your floor for the past 5 years. She has been complaining of pain, burning, and tingling on her left side. Today, you observe fluid-filled blisters wrapping around the left side of her torso in a single line. The physician diagnoses her with shingles and places her on contact precautions. -The bacteriophage multiplication cycle is similar to that of an animal virus with the exception of uncoating.Uncoating does not occur because


A) they utilize specific receptors on the bacterial surface to adsorb.
B) the viral nucleic acid penetrates the host after being injected through a rigid tube inserted through the bacterial cell membrane and wall.
C) the viral nucleic acid enters the host cell through transformation.
D) the virus is engulfed by the cell and enclosed in a vacuole via endocytosis.

E) C) and D)
F) None of the above

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Which of the following occurs during assembly?


A) Nucleocapsid is formed.
B) New viral nucleic acid is formed.
C) Viral spikes insert in host cell membrane.
D) A nucleocapsid is formed and viral spikes insert in host cell membrane.
E) All of the choices occur.

F) A) and D)
G) All of the above

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Infectious protein particles are called


A) viroids.
B) phages.
C) prions.
D) oncogenic viruses.
E) spikes.

F) A) and D)
G) B) and C)

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Viruses are not filterable.

A) True
B) False

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Which of the following is not a typical capsid shape?


A) tetrahedral
B) complex
C) helical
D) icosahedron
E) All of the choices are capsid shapes.

F) B) and D)
G) A) and E)

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Viruses are unable to multiply outside of a host cell.

A) True
B) False

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Two noncellular agents,smaller than viruses,are the infectious proteins called _____ and the infectious RNA strands called _____.


A) prions,capsomeres
B) virions,prions
C) viroids,phages
D) prions,phages
E) prions,viroids

F) A) and B)
G) A) and E)

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Viruses are used to produce vaccines for prevention of certain viral infections.

A) True
B) False

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Viruses acquire envelopes around their nucleocapsids during


A) replication.
B) assembly.
C) adsorption.
D) release.
E) penetration.

F) None of the above
G) All of the above

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Viruses that cause infection resulting in alternating periods of activity with symptoms and inactivity without symptoms are called


A) latent.
B) oncogenic.
C) prions.
D) viroids.
E) delta agents.

F) A) and B)
G) C) and E)

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Mammalian viruses capable of starting tumors are


A) chronic latent viruses.
B) oncoviruses.
C) syncytia.
D) inclusion bodies.
E) cytiopathic.

F) C) and D)
G) B) and C)

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. 5-month-old Emily Harter presented to the pediatrician’s office with a fever, dyspnea (labored breathing) , wheezing, nasal flaring, and a harsh cough. Rapid testing of nasal swabs obtained from Emily revealed RSV disease. Mrs. Harter is distraught to learn that her daughter will be admitted to the hospital, and will receive intravenous hydration and oxygen therapy. -RSV belongs to which virus family?


A) Poxviridae
B) Picornaviridae
C) Filoviridae
D) Reoviridae

E) A) and C)
F) B) and D)

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One of the principal capsid shapes is a 20-sided figure with 12 evenly spaced corners referred to as a(n) _____ capsid.


A) spiked
B) complex
C) icosahedral
D) helical
E) buckeyball

F) B) and C)
G) D) and E)

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Viral spikes


A) are always present on enveloped viruses.
B) protrude from the envelope.
C) block attachment between virus and host.
D) are derived from host proteins.
E) All of the choices are correct.

F) A) and E)
G) B) and C)

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Viruses are simple,noncellular,and lack mRNA.

A) True
B) False

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