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Traits that are carried on the X chromosome are said to be _________________.


A) autosomal
B) gametal
C) sex-linked
D) alleles

E) None of the above
F) C) and D)

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If you needed to order genes on a chromosome,you would perform


A) a test cross.
B) a two-point cross.
C) a three-point cross.
D) a SNP test.

E) B) and C)
F) A) and D)

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A test cross can be used to do all of the following except


A) determine whether an individual that displays a dominant phenotype is homozygous for the trait.
B) determine whether an individual that displays a dominant phenotype is heterozygous for the trait.
C) gather genotype information from phenotype information.
D) identify the chromosome on which a gene is locateD.

E) B) and C)
F) A) and B)

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A deletion of a particular stretch of chromosome 15 can cause either Prader-Willi syndrome or Angelman syndrome,depending on


A) the parental origin of the normal and deleted chromosome.
B) whether or not the region is methylated properly.
C) whether a translocation event has occurred.
D) whether a nondisjunction event has occurreD.

E) A) and D)
F) A) and C)

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The white eye mutation in Drosophila was shown to be sex-linked and caused by a gene residing on chromosome


A) X.
B) Y.
C) 1.
D) 2.
E) autosomE.

F) B) and C)
G) A) and E)

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If a XY individual had a deletion of the SYR gene,they would


A) develop as a female.
B) have both male and female characteristics.
C) have ambiguous genitalia.
D) develop as a male.

E) All of the above
F) None of the above

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Why is mitochondrial DNA not a unique identifier?


A) Mitochondrial DNA is inherited through the paternal lineage.All offspring inherit their father's mitochondria,and therefore the same mitochondrial DNA.As a result,all family members that share a paternal lineage would have the same mitochondrial DNA.Mitochondrial DNA can therefore be used to confirm or eliminate a person's relationship within a paternal line,but cannot be used to identify a specific individual.
B) Mitochondrial DNA is inherited through the maternal lineage.All offspring inherit their mother's mitochondria,and therefore the same mitochondrial DNA.As a result,all family members that share a maternal lineage would have the same mitochondrial DNA.Mitochondrial DNA can therefore be used to confirm or eliminate a person's relationship within a maternal line,but cannot be used to identify a specific individual.
C) Mitochondrial DNA is inherited through the maternal lineage.All female offspring inherit their mother's mitochondria,and therefore the same mitochondrial DNA.As a result,all female family members that share a maternal lineage would have the same mitochondrial DNA.Mitochondrial DNA can therefore be used to confirm or eliminate a person's relationship within a maternal line,but cannot be used to identify a specific individual.

D) A) and B)
E) All of the above

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The classic experiments performed by Creighton and McClintock in Maize


A) provided the initial evidence for recombination.
B) provided evidence for linkage between genes.
C) allowed for the establishment of the first genetic map.
D) provided evidence for the physical exchange of genetic material.

E) A) and B)
F) B) and D)

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In Drosophila,the sex of an individual is influenced by the number of copies of which chromosome?


A) autosome
B) X
C) 1
D) 2
E) white

F) A) and E)
G) A) and D)

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The geneticist who discovered the white eye mutation in Drosophila and helped establish that genes are carried on chromosomes was


A) Mendel.
B) Sutton.
C) Sturtevant.
D) Janssens.
E) Morgan.

F) A) and E)
G) B) and E)

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Nondisjunction of autosomes can lead to all of the following except


A) aneuploidy.
B) monosomy.
C) trisomy.
D) euploidy.

E) A) and B)
F) None of the above

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In Drosophila,dosage compensation is controlled by the male-specific lethal (MSL) complex consisting of MSL proteins and roX RNAs.Based on what you know about dosage compensation,the role of the MSL complex would be to


A) increase the level of expression on the X chromosome approximately 2 fold.
B) increase the level of expression on the X chromosome approximately 50%.
C) decrease the level of expression on the X chromosome approximately 2 fold.
D) decrease the level of expression on the X chromosome approximately 50%.

E) None of the above
F) C) and D)

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Given that bw and hv are closely linked,which of the following genotypic ratios can you expect to find in the F2 generation?


A) 1:2:1
B) 1:1:1:1
C) 9:3:3:1
D) 3:1

E) A) and B)
F) A) and C)

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What would be the results of a test cross with the F1 flies?


A) 1 brown,thin: 1 red,heavy
B) 1 brown,heavy: 1 red,thin
C) 1 brown,thin: 2 red,thin: 1 red,heavy
D) 1 brown,heavy: 2 red,thin: 1 red,thin

E) A) and C)
F) B) and D)

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In humans,if a non-disjunction event led to an individual with a genotype of XXY,they would


A) be female because they have two X chromosomes.
B) be male because they have a Y chromosome.
C) display both male and female characteristics.
D) not survive.

E) All of the above
F) C) and D)

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Over time,natural selection eliminates individuals with detrimental phenotypes from a population.However,there are several examples in the human population in which harmful genetic polymorphisms are maintained.Why?


A) Individuals with two wild type alleles have advantages over individuals carrying the harmful allele.
B) Individuals with two harmful alleles have advantages over individuals carrying one copy of the harmful allele.
C) Homozygous individuals have some other advantage over individuals with two wild type alleles.
D) Heterozygous individuals have some other advantage over individuals with two wild type alleles.

E) B) and C)
F) None of the above

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Which offspring will inherit all their mitochondria DNA from their mother and none from their father?


A) daughters
B) sons
C) both sons and daughters
D) Mitochondria DNA is inherited from both parents

E) All of the above
F) B) and C)

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Occasionally,chromosomes fail to separate during meiosis,leading to a condition in which the diploid number is not normal.This phenomenon is called


A) epistasis.
B) nondisjunction.
C) disjunction.
D) pleiotropy.
E) autosomy.

F) A) and E)
G) A) and B)

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Sickle cell anemia is caused by a defect in the


A) oxygen carrying pigment hemoglobin.
B) protein makeup in the liver.
C) sticky sides of the red blood cells.
D) allele for the production of mucus in the lungs.

E) B) and C)
F) A) and B)

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Organisms generally have many more genes that assort independently than the number of chromosomes.This phenomenon is due to


A) independent assortment.
B) segregation.
C) crossing over.
D) epistasis.
E) pleiotropy.

F) C) and D)
G) A) and B)

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