Question 1

What is the relationship between recombination frequency and true genetic distance on a chromosome?

Accepted Answer

A)  As genetic distance increases,the recombination frequency increases in a linear fashion.
B)  As genetic distance increases,the recombination frequency increases,but never in a linear fashion.
C)  As genetic distance increases,the recombination frequency first increases in a linear fashion,but then levels off to a frequency of 0.5.
D)  As genetic distance increases,the recombination frequency first increases,but then decreases.E) A) and C)
F) A) and B)

Question 2

How did the development of anonymous markers aid in the production of a human genetic map?

Accepted Answer

A)  Anonymous markers are genetic markers that do not cause a detectable phenotype,but can be detected by molecular techniques.The markers correspond to specific and unique chromosomal regions,thereby allowing for the identification and ordering of particular segments of DNA.Such information was essential to the generation of a human genetic map.
B)  Anonymous markers are genetic markers that cause a detectable phenotype and can't be detected by molecular techniques.The markers correspond to specific and unique chromosomal regions,thereby allowing for the identification and ordering of particular segments of DNA.Such information was essential to the generation of a human genetic map.
C)  Anonymous markers are genetic markers that do not cause a detectable phenotype,but can be detected by molecular techniques.The markers correspond to specific and unique genetic regions,thereby allowing for the identification and ordering of particular segments of the chromosome.Such information was essential to the generation of a human genetic map.D) B) and C)
E) A) and C)

Question 3

A 39-year-old woman is in her sixth week of pregnancy.Due to her advanced maternal age,she is at high risk for having a baby with Down's syndrome.She would like to find out as early as possible whether or not her baby has Down's syndrome.Her doctor suggests

Accepted Answer

A)  amniocentesis.
B)  genetic counseling.
C)  chorionic villi sampling.
D)  a pedigree analysis.E) A) and B)
F) A) and C)

Question 4

Genetic differences between individuals in a population are called

Accepted Answer

A)  markers.
B)  alleles.
C)  polymorphisms.
D)  genetic disorders.E) All of the above
F) A) and B)

Question 5

In sickle cell anemia,the defective hemoglobin differs from the normal hemoglobin by

Accepted Answer

A)  the color of the pigment.
B)  the size of the molecule.
C)  a single amino acid substitution.
D)  the total number of amino acids.
E)  the type of blood cell it is found in.F) D) and E)
G) All of the above

Question 6

In a two-point cross to map genes A and B,you obtained 98 recombinant flies out of a total of 730 progeny.How far apart are these genes?

Accepted Answer

A)  11.8 cM
B)  13.4 cM
C)  98 cM
D)  632 cME) All of the above
F) None of the above

Question 7

Huntington's disease is caused by an autosomal dominant allele.It is a lethal disease,but it persists in the human population.Which of the following statements best describes why?

Accepted Answer

A)  Huntington's disease is sex-linked and every human has at least one X chromosome;thus,the chances are extremely high for this allele to be maintained in the human population.
B)  Huntington's disease presents symptoms that resemble cases reflecting a lack of dominance in some individuals;in those cases,the allele is passed on to the offspring.
C)  While lethal to a parent,Huntington's disease will not be lethal to the offspring since it can skip a generation.
D)  Huntington's disease presents symptoms in humans after many have already reproduced;therefore,they are unaware that they passed on Huntington's disease.
E)  Huntington's disease can be treated in humans that are heterozygous for the condition,but individuals who are homozygous cannot receive treatments;thus,they pass on the alleles to their offspring.F) A) and B)
G) A) and C)

Question 8

_______________ is a human hereditary disease that is caused by a dominant allele but does not show up in affected individuals until they are in middle age.

Accepted Answer

A)  Cystic fibrosis
B)  Sickle cell anemia
C)  Tay-Sachs disease
D)  Huntington's disease
E)  HemophiliaF) B) and C)
G) B) and E)

Question 9

The theory of chromosomal inheritance was first proposed by

Accepted Answer

A)  Mendel.
B)  Morgan.
C)  Knight.
D)  Sutton.
E)  Stern.F) A) and E)
G) B) and E)

Question 10

Morgan's student Sturtevant demonstrated that the recombination frequencies between a series of linked genes is additive.Examine the following recombination data from Sturtevant,and determine the proper order of the genes on the Drosophila X chromosome.Assume y is in the 0.0 position.

Accepted Answer

A)  y m v w
B)  y w v m
C)  y m w v
D)  y w m vE) A) and B)
F) B) and D)

Question 11

Humans who have lost even one copy of an autosome are called

Accepted Answer

A)  tetrasomics.
B)  trisomics.
C)  bisomics.
D)  monosomics.
E)  nullisomics.F) B) and E)
G) A) and B)

Question 12

If a female was a carrier for sex-linked color blindness,what percentage of her male children would also be color blind?

Accepted Answer

A)  0%
B)  25%
C)  50%
D)  100%E) C) and D)
F) B) and C)

Question 13

If a human female has two Barr bodies,it is almost certain that

Accepted Answer

A)  her father had at least one Barr body.
B)  her mother also had two Barr bodies.
C)  she developed from a fertilized egg with 3 X chromosomes.
D)  she is actually a male with female characteristics.
E)  she is genetically a normal fertile femalE.F) A) and D)
G) A) and C) C

Question 14

You want to determine the temperature at which one would obtain a ratio of 1:1 of each gender.Which of the following conditions would (1) best address this question,and (2) is most scientifically sound?

Accepted Answer

A)  Grow turtles in two different incubators at temperatures of 22ºC and 30ºC.
B)  Grow turtles in three different incubators at temperatures of 26ºC,28ºC,and 30ºC.
C)  Grow turtles in four different incubators at temperatures of 24ºC,26ºC,28ºC,and 30ºC.
D)  Grow turtles in five different incubators at temperatures of 22ºC,24ºC,26ºC,28ºC,and 30ºC.E) None of the above
F) All of the above D

Question 15

A fatal human disease in which the faulty gene codes for abnormal gland secretions leading to liver and lung failure is called ________________.

Accepted Answer

A)  lung cancer
B)  multiple sclerosis
C)  muscular dystrophy
D)  cystic fibrosisE) All of the above
F) B) and C)

Question 16

A genetic _____ contains the distances between the gene loci measured in terms of the frequency of recombination.

Accepted Answer

A)  map
B)  profile
C)  construct
D)  cloneE) A) and D)
F) A) and C)

Question 17

A human female with only one X chromosome is said to have a condition called

Accepted Answer

A)  Alzheimer's disease.
B)  hemophilia.
C)  Turner syndrome.
D)  Klinefelter syndrome.
E)  Down syndromE.F) A) and B)
G) B) and E) C

Question 18

A same-sex couple wants to have a child in which they both contribute genetically to the offspring.Assuming it was technically possible to replace the DNA found in a sperm with female DNA,or DNA found in the egg with male DNA,what other scientific obstacle must be overcome?

Accepted Answer

A)  sex determination
B)  translocation events
C)  genetic imprinting
D)  nondisjunction eventsE) B) and D)
F) All of the above

Question 19

Based on this observation,

Accepted Answer

A)  you conclude that sex-determination is temperature dependent.
B)  you hypothesize that only male turtles survive at room temperature.
C)  you hypothesize that sex-determination in turtles in influenced by temperature,but you need more data to be sure.
D)  you realize that it was a coincidence that only males were born since gender is always determined by sex chromosomes.E) B) and C)
F) A) and D)

Question 20

The most common fatal genetic disorder of Caucasians is

Accepted Answer

A)  cholerA.
B)  cystic fibrosis.
C)  hemophilia.
D)  sickle cell anemia.
E)  muscular dystrophy.F) All of the above
G) C) and D)

Exam 13: Chromosomes Mapping and the Meiosis - Inheritance Connection

What is the relationship between recombination frequency and true genetic distance on a chromosome?

Correct AnswerverifiedShow Answer

How did the development of anonymous markers aid in the production of a human genetic map?

Correct AnswerverifiedShow Answer

A 39-year-old woman is in her sixth week of pregnancy.Due to her advanced maternal age,she is at high risk for having a baby with Down's syndrome.She would like to find out as early as possible whether or not her baby has Down's syndrome.Her doctor suggests

Correct AnswerverifiedShow Answer

Genetic differences between individuals in a population are called

Correct AnswerverifiedShow Answer

In sickle cell anemia,the defective hemoglobin differs from the normal hemoglobin by

Correct AnswerverifiedShow Answer

In a two-point cross to map genes A and B,you obtained 98 recombinant flies out of a total of 730 progeny.How far apart are these genes?

Correct AnswerverifiedShow Answer

Huntington's disease is caused by an autosomal dominant allele.It is a lethal disease,but it persists in the human population.Which of the following statements best describes why?

Correct AnswerverifiedShow Answer

_______________ is a human hereditary disease that is caused by a dominant allele but does not show up in affected individuals until they are in middle age.

Correct AnswerverifiedShow Answer

The theory of chromosomal inheritance was first proposed by

Correct AnswerverifiedShow Answer

Morgan's student Sturtevant demonstrated that the recombination frequencies between a series of linked genes is additive.Examine the following recombination data from Sturtevant,and determine the proper order of the genes on the Drosophila X chromosome.Assume y is in the 0.0 position.

Correct AnswerverifiedShow Answer

Humans who have lost even one copy of an autosome are called

Correct AnswerverifiedShow Answer

If a female was a carrier for sex-linked color blindness,what percentage of her male children would also be color blind?

Correct AnswerverifiedShow Answer

If a human female has two Barr bodies,it is almost certain that

Correct AnswerverifiedC

You want to determine the temperature at which one would obtain a ratio of 1:1 of each gender.Which of the following conditions would (1) best address this question,and (2) is most scientifically sound?

Correct AnswerverifiedD

A fatal human disease in which the faulty gene codes for abnormal gland secretions leading to liver and lung failure is called ________________.

Correct AnswerverifiedShow Answer

A genetic _____ contains the distances between the gene loci measured in terms of the frequency of recombination.

Correct AnswerverifiedShow Answer

A human female with only one X chromosome is said to have a condition called

Correct AnswerverifiedC

A same-sex couple wants to have a child in which they both contribute genetically to the offspring.Assuming it was technically possible to replace the DNA found in a sperm with female DNA,or DNA found in the egg with male DNA,what other scientific obstacle must be overcome?

Correct AnswerverifiedShow Answer

Based on this observation,

Correct AnswerverifiedShow Answer

The most common fatal genetic disorder of Caucasians is

Correct AnswerverifiedShow Answer

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