Question 1

Traditionally,toxicology studies have involved numerous bioassays on rodents.However,a more reliable and reproducible approach to study the genome-wide effects of a toxin,one could use

Accepted Answer

A)  a protein microarray.
B)  functional genomics.
C)  a yeast two-hybrid screen.
D)  a DNA microarray.E) C) and D)
F) All of the above

Question 2

You can do all of the following using comparative genomics except

Accepted Answer

A)  draw particular conclusions about species.
B)  draw general conclusions about evolution.
C)  infer function about an unsequenced genome using synteny.
D)  develop a haplotype map.E) None of the above
F) B) and C)

Question 3

After years of work,a researcher identified a novel protein that binds to serotonin receptors in mouse brain.Which of the following explanations regarding gene patents is most appropriate in this case?

Accepted Answer

A)  The researcher has clearly defined the function of the gene.The gene itself can be patented.
B)  The researcher has not yet clearly defined the function of the gene.However,when the function is clearly identified,the gene itself can be patented.
C)  The researcher has clearly defined the function of the gene.Thus,the use of the gene can be patented.
D)  The researcher has not yet clearly defined the function of the gene.However,when the function is clearly identified,the use of the gene can be patenteD.E) A) and D)
F) A) and C)

Question 4

_________ is another term used to describe genome science.

Accepted Answer

A)  Genomics
B)  Proteomics
C)  Chromosomics
D)  DianeticsE) A) and C)
F) None of the above

Question 5

Mobile bits of DNA that can jump from one location on a chromosome to another location are called

Accepted Answer

A)  simple sequence repeats.
B)  transposons.
C)  exons.
D)  introns.
E)  pseudogenes.F) B) and C)
G) D) and E)

Question 6

________ are silent copies of genes that have been inactivated by mutations.

Accepted Answer

A)  Pseudogenes
B)  Clones
C)  Exons
D)  IntronsE) A) and D)
F) A) and C)

Question 7

As a scientist working for an antibioterrorism task force,you are asked to evaluate some biological samples for presence of Yersinia pestis,the organism that causes plague.After confirming that the samples did,indeed,contain Y.pestis,you instruct your team to begin sequencing the strain.Given that the genome sequence of Y.pestis is already known,why did you instruct your team to sequence this strain?

Accepted Answer

A)  to confirm the original genome sequence and gather possible information on the origin of the strain
B)  to establish the course of infection and determine whether the strain has been genetically engineered
C)  to gather possible information on the origin of the strain and determine whether the strain has been genetically engineered
D)  to establish the SNPs necessary to confirm infection from this strainE) A) and D)
F) C) and D)

Question 8

To be classed as a polymorphism,a SNP must be present in

Accepted Answer

A)  every draft sequence of the species being investigated.
B)  every finished sequence of the species being investigated.
C)  at least one genome of the species being investigated.
D)  at least 1% of the population of the species being investigateD.E) A) and C)
F) None of the above

Question 9

A transgene is

Accepted Answer

A)  hard to destroy once inserted into a genome.
B)  hard to study because of its transposons.
C)  created by several of the DNA motifs.
D)  an inserted foreign gene.
E)  a result of endosymbiosis.F) A) and B)
G) A) and E)

Question 10

Non-coding DNA regions within a gene are referred to as

Accepted Answer

A)  introns.
B)  exons.
C)  templates.
D)  transposons.
E)  pseudogenes.F) B) and D)
G) A) and B)

Question 11

All of the following would be useful in an effort to construct a physical map of a genome except

Accepted Answer

A)  BAC end sequences.
B)  BLAST data.
C)  ESTs.
D)  STS markers.E) C) and D)
F) All of the above

Question 12

Homologous regions of DNA can vary slightly in base-pair composition among individuals in a population.When a homologous stretch of DNA is cut with restriction enzymes in different individuals,fragments of different lengths are produced.These fragments are called

Accepted Answer

A)  landmarks of DNA sequencing.
B)  contig fragments.
C)  single length polymorphisms.
D)  restriction fragments length polymorphisms.
E)  sequence-tagged site fragments.F) B) and E)
G) C) and D)

Question 13

What is the most significant research finding from the rice genome project?

Accepted Answer

A)  The similarity between the rice genome and other cereal crops will help scientists to move faster to develop genome data for other cereal crops.
B)  The rice genome was found to be larger than that of humans.
C)  The development of Golden Rice.
D)  The genome data can be used to develop more nutritional rice.E) B) and C)
F) A) and D)

Question 14

The ends of chromosomes are called _________.

Accepted Answer

A)  telomeres
B)  centromeres
C)  caps
D)  DNA terminiE) B) and D)
F) A) and C)

Question 15

Some regions of chromosomes remain highly condensed,tightly coiled,and untranscribed throughout the cell cycle.These regions are referred called

Accepted Answer

A)  transposable elements.
B)  single sequence repeats.
C)  non-coding DNA.
D)  short interspersed elements.
E)  constitutive heterchromatin.F) A) and C)
G) A) and D)

Question 16

Which of the following statements regarding genomes is true?

Accepted Answer

A)  In general,eukaryotic genomes are larger than prokaryotic genomes.
B)  In general,eukaryotic genomes are smaller than prokaryotic genomes.
C)  The size of the organism determines the size of the genome.
D)  Larger and more complex organisms have more genes than smaller,less complex organisms.E) C) and D)
F) All of the above

Question 17

Inactive genes that have lost their function due to mutations are called

Accepted Answer

A)  introns.
B)  exons.
C)  templates.
D)  transposons.
E)  pseudogenes.F) A) and E)
G) A) and B)

Question 18

Which of the following organisms has the greatest number of genes?

Accepted Answer

A)  rice
B)  human
C)  fruit fly
D)  yeastE) B) and C)
F) None of the above

Question 19

Sequences of DNA assembled by identifying overlaps among smaller DNA segments are known as

Accepted Answer

A)  single strand polymorphisms.
B)  synteny.
C)  draft sequences.
D)  proteone.
E)  contig.F) B) and C)
G) B) and E)

Question 20

As the director of a new non-profit functional genomics research center,it is your job to oversee the set up of laboratories necessary to achieve the research goals of the center.Therefore,you plan to include all of the following,except a

Accepted Answer

A)  DNA microarray facility.
B)  proteomics laB.
C)  sequence annotation facility.
D)  mutagenesis facility.E) B) and C)
F) A) and C)

Exam 18: Genomics

The ends of chromosomes are called _________.

Correct Answer
verified

Traditionally,toxicology studies have involved numerous bioassays on rodents.However,a more reliable and reproducible approach to study the genome-wide effects of a toxin,one could use

Correct Answer
verified

After years of work,a researcher identified a novel protein that binds to serotonin receptors in mouse brain.Which of the following explanations regarding gene patents is most appropriate in this case?

Correct Answer
verified

As the director of a new non-profit functional genomics research center,it is your job to oversee the set up of laboratories necessary to achieve the research goals of the center.Therefore,you plan to include all of the following,except a

Correct Answer
verified

What is the most significant research finding from the rice genome project?

Correct Answer
verified

Non-coding DNA regions within a gene are referred to as

Correct Answer
verified

Some regions of chromosomes remain highly condensed,tightly coiled,and untranscribed throughout the cell cycle.These regions are referred called

Correct Answer
verified

Correct Answer
verified

All of the following would be useful in an effort to construct a physical map of a genome except

Correct Answer
verified

________ are silent copies of genes that have been inactivated by mutations.

Correct Answer
verified

To be classed as a polymorphism,a SNP must be present in

Correct Answer
verified

Sequences of DNA assembled by identifying overlaps among smaller DNA segments are known as

Correct Answer
verified

Mobile bits of DNA that can jump from one location on a chromosome to another location are called

Correct Answer
verified

Inactive genes that have lost their function due to mutations are called

Correct Answer
verified

Which of the following statements regarding genomes is true?

Correct Answer
verified

_________ is another term used to describe genome science.

Correct Answer
verified

A transgene is

Correct Answer
verified

Which of the following organisms has the greatest number of genes?

Correct Answer
verified

You can do all of the following using comparative genomics except

Correct Answer
verified

Homologous regions of DNA can vary slightly in base-pair composition among individuals in a population.When a homologous stretch of DNA is cut with restriction enzymes in different individuals,fragments of different lengths are produced.These fragments are called

Correct Answer
verified

Exam 18: Genomics

The ends of chromosomes are called _________.

Correct AnswerverifiedShow Answer

Traditionally,toxicology studies have involved numerous bioassays on rodents.However,a more reliable and reproducible approach to study the genome-wide effects of a toxin,one could use

Correct AnswerverifiedShow Answer

After years of work,a researcher identified a novel protein that binds to serotonin receptors in mouse brain.Which of the following explanations regarding gene patents is most appropriate in this case?

Correct AnswerverifiedShow Answer

As the director of a new non-profit functional genomics research center,it is your job to oversee the set up of laboratories necessary to achieve the research goals of the center.Therefore,you plan to include all of the following,except a

Correct AnswerverifiedShow Answer

What is the most significant research finding from the rice genome project?

Correct AnswerverifiedShow Answer

Non-coding DNA regions within a gene are referred to as

Correct AnswerverifiedShow Answer

Some regions of chromosomes remain highly condensed,tightly coiled,and untranscribed throughout the cell cycle.These regions are referred called

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

All of the following would be useful in an effort to construct a physical map of a genome except

Correct AnswerverifiedShow Answer

________ are silent copies of genes that have been inactivated by mutations.

Correct AnswerverifiedShow Answer

To be classed as a polymorphism,a SNP must be present in

Correct AnswerverifiedShow Answer

Sequences of DNA assembled by identifying overlaps among smaller DNA segments are known as

Correct AnswerverifiedShow Answer

Mobile bits of DNA that can jump from one location on a chromosome to another location are called

Correct AnswerverifiedShow Answer

Inactive genes that have lost their function due to mutations are called

Correct AnswerverifiedShow Answer

Which of the following statements regarding genomes is true?

Correct AnswerverifiedShow Answer

_________ is another term used to describe genome science.

Correct AnswerverifiedShow Answer

A transgene is

Correct AnswerverifiedShow Answer

Which of the following organisms has the greatest number of genes?

Correct AnswerverifiedShow Answer

You can do all of the following using comparative genomics except

Correct AnswerverifiedShow Answer

Homologous regions of DNA can vary slightly in base-pair composition among individuals in a population.When a homologous stretch of DNA is cut with restriction enzymes in different individuals,fragments of different lengths are produced.These fragments are called

Correct AnswerverifiedShow Answer

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