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A xenograft is graft tissue from a donor of one species transplanted to a recipient of another species.

A) True
B) False

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What will be the immediate action of an allergen when it enters that body for a second time?


A) Degranulation
B) Bonding of allergen to adjacent IgE binding sites on mast cells and basophils
C) Binding of IgE by the Fc region to mast cells and basophils
D) Histamine acts on smooth muscle
E) Prostaglandins cause vasodilation and increased vascular permeability

F) B) and C)
G) C) and D)

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A seasonal reaction to inhaled allergens is ________.


A) atopic dermatitis
B) eczema
C) allergic rhinitis
D) asthma
E) anaphylaxis

F) B) and D)
G) A) and E)

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Contact dermatitis involves ________.


A) a sensitizing and provocative dose
B) an allergen entering the skin
C) T lymphocytes secreting inflammatory cytokines
D) itchy papules and blisters
E) All of the choices are correct.

F) A) and E)
G) B) and C)

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Each of the following is an autoimmune disease except ________.


A) systemic lupus erythematosus
B) Graves' disease
C) type I diabetes
D) metastatic cancer
E) rheumatic fever

F) C) and D)
G) A) and C)

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Which event is the process of releasing chemical mediators?


A) Degranulation
B) Bonding of allergen to adjacent IgE binding sites on mast cells and basophils
C) Binding of IgE by the Fc region to mast cells and basophils
D) Histamine acts on smooth muscle
E) Prostaglandins cause vasodilation and increased vascular permeability

F) B) and D)
G) None of the above

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Bee sting venom is considered to be which type of allergen?


A) Ingestant
B) Inhalant
C) Injectant
D) Contactant
E) None of the choices are correct.

F) C) and D)
G) A) and B)

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The potential for hemolytic disease of the newborn occurs when ________.


A) maternal Rh⁺ cells enter an Rh⁻ fetus
B) fetal Rh⁺ cells enter an Rh⁻ mother
C) maternal Rh˗ cells enter an Rh⁺ fetus
D) fetal Rh˗ cells enter an Rh⁺ mother
E) fetal Rh⁺ cells enter an Rh⁺ mother

F) B) and D)
G) B) and C)

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During graft rejection,cytotoxic T cells of the recipient recognize and respond to foreign class I MHC receptors on the grafted cells.

A) True
B) False

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Histamine causes all of the following except ________.


A) increased sensitivity to pain
B) constriction of smooth muscle of bronchi and the intestine
C) relaxes vascular smooth muscle
D) wheal and flare reaction in skin
E) pruritus and headache

F) A) and D)
G) D) and E)

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A viral infection can cause type I diabetes mellitus.

A) True
B) False

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Type II hypersensitivities differ from type III in that ________.


A) type II hypersensitivity involves the activation of complement proteins that attack and lyse cells,whereas type III involves the formation of immune complexes causing chronic inflammation
B) type II hypersensitivity involves the formation of immune complexes causing chronic inflammation,whereas type III involves the activation of complement proteins that attack and lyse cells
C) type II hypersensitivity involves the formation of IgM antibodies that attack tissues,whereas type III involves IgE causing degranulation of mast cells
D) type II hypersensitivity involves B cells whereas type III involves the activation and sensitization of cytotoxic T cells

E) C) and D)
F) B) and D)

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A systemic,sometimes fatal reaction with airway obstruction and circulatory collapse is ________.


A) delayed
B) T-cell mediated
C) atopic
D) antibody mediated
E) systemic anaphylactic

F) A) and B)
G) A) and C)

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A 28-year-old woman is 30 weeks pregnant with her second child and is being seen for a scheduled obstetric visit. Her first pregnancy and delivery was uncomplicated, and she has a healthy 2-year-old girl. It is known that the mother is Rh-, and this child could be at risk for hemolytic disease of the newborn. She received RhoGAM with her first pregnancy. -What intervention would the RN expect during this visit?  


A) Fetal blood type testing to determine if RhoGAM is indicated
B) Administration of first dose of RhoGAM
C) Nothing,since it is not known if the fetus is Rh+
D) Plan for first dose of RhoGAM immediately after birth

E) A) and B)
F) B) and C)

Correct Answer

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In the theory for allergic desensitization,which immunoglobulin blocks the allergen from binding with IgE?


A) IgE
B) IgG
C) IgA
D) IgD
E) IgM

F) C) and E)
G) A) and B)

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Which of the following is not a theory to explain the origin of autoimmune diseases?


A) Sequestered antigen theory
B) Clonal selection theory
C) Theory of immune deficiency
D) Viral infection theory
E) All of the choices are possible theories.

F) B) and C)
G) A) and E)

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Large quantities of antibodies that react to the second entry of antigen and lead to formation of antigen-antibody complexes occurs in ________.


A) serum sickness
B) delayed hypersensitivity
C) anaphylaxis
D) hemolytic disease of the newborn
E) All of the choices are correct.

F) C) and D)
G) B) and D)

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Which type(s) of hypersensitivity is IgG involved with?


A) Anaphylaxis
B) Antibody mediated
C) Immune complex mediated
D) Both anaphylaxis and antibody mediated
E) Both antibody mediated and immune complex mediated

F) D) and E)
G) C) and E)

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Fungal spores and animal dander are considered to be which type of allergen?


A) Ingestant
B) Inhalant
C) Injectant
D) Contactant
E) None of the choices are correct.

F) B) and C)
G) A) and B)

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A 9-year-old male presents to the emergency room complaining of "chest tightness" and difficulty breathing. The RN notes that he is frequently coughing and wheezes are ausculated in all lung fields. His chest x-ray shows a flattened diaphragm and overexpanded lungs. The patient's mother reports that he had five episodes like this one over the past few years, but none this bad. Recently, the patient has had more frequent episodes of difficulty breathing and coughing, each lasting for a few hours. He does not take any medications at home. -Based on the patient's symptoms,which of the following is the most likely diagnosis?  


A) Asthma
B) Hay fever
C) Seasonal allergy
D) Eczema

E) All of the above
F) A) and C)

Correct Answer

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