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Mr. Miller has been hospitalized for the flu. The flu virus increases membrane permeability to potassium. You would expect his cells to


A) depolarize.
B) repolarize.
C) isopolarize.
D) hyperpolarize.
E) hypopolarize.

F) A) and E)
G) B) and D)

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Match the term with the correct definition. -Action Potential


A) a small change in the resting membrane potential confined to a small area
B) a charge difference across the plasma membrane when the cell is in an unstimulated state
C) a larger change in resting membrane potential that spreads over entire surface of a cell
D) membrane becomes more positive when sodium ions diffuse into cell
E) return to the resting membrane potential

F) A) and B)
G) D) and E)

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Gray matter on the surface of the brain is/are called


A) the cortex.
B) nuclei.
C) ganglia.
D) tracts.

E) A) and B)
F) A) and C)

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A

Arrange the events of synaptic transmission in correct sequence. (1) sodium ions diffuse into the cell and cause a local potential (2) neurotransmitter binds with receptor on postsynaptic cell (3) neurotransmitter diffuses across the synaptic cleft (4) membrane permeability to sodium ions on postsynaptic cell increases (5) action potential causes release of neurotransmitter


A) 5, 2, 3, 4, 1
B) 5, 2, 3, 1, 4
C) 5, 3, 4, 1, 2
D) 5, 4, 3, 2, 1
E) 5, 3, 2, 4, 1

F) C) and D)
G) A) and C)

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Identify structure "B" on the neuron.


A) Schwann cell
B) Node of Ranvier
C) neuron cell body (soma)
D) dendrites
E) axon

F) D) and E)
G) A) and B)

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Depolarization of the nerve cell membrane occurs when there is a rapid influx (inflow) of


A) potassium ions.
B) chloride ions.
C) calcium ions.
D) sodium ions.
E) proteins.

F) A) and B)
G) B) and C)

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Identify structure "C" on the neuron.


A) Schwann cell
B) Node of Ranvier
C) neuron cell body (soma)
D) dendrites
E) axon

F) A) and B)
G) A) and C)

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Saltatory conduction of an action potential means that


A) once one action potential is created, it moves down the axon.
B) the whole axon depolarizes at the same time.
C) one action potential stimulates the production of a new action potential at the adjacent site.
D) an action potential is conducted from one node of Ranvier to the next node.

E) None of the above
F) A) and B)

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A local potential


A) does not occur until threshold.
B) transmits information from one cell to another.
C) might be a depolarization event but cannot be a hyperpolarization event.
D) increases or decreases in direct proportion to the stimulus strength.
E) does not alter resting membrane potential.

F) A) and B)
G) A) and C)

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Viagra is used to treat erectile dysfunction by prolonging the effects of _____ on blood vessels.


A) substance P
B) dopamine
C) GABA
D) nitric oxide (NO)

E) B) and C)
F) A) and C)

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The autonomic nervous system


A) stimulates skeletal muscle contractions.
B) has two sets of neurons in a series.
C) is involved in problem solving.
D) is under voluntary control.
E) does not include the central nervous system.

F) A) and D)
G) A) and E)

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B

A decrease in the number of voltage-gated Ca2+ ion channels in the presynaptic terminal would


A) enhance transmission across the synapse.
B) reduce or inhibit transmission across the synapse.
C) have no effect on transmission across the synapse.
D) alter receptors on the postsynaptic membrane.
E) increase exocytosis.

F) A) and B)
G) None of the above

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If five action potentials arrive at the same synapse in very close succession, which of the following would occur?


A) The direction of the action potential is reversed.
B) Temporal summation occurs.
C) Spatial summation occurs.
D) Hyperpolarization occurs.
E) Depolarization always occurs.

F) A) and E)
G) A) and C)

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Continuous conduction of an action potential means that


A) once one action potential is created, it moves down the axon.
B) the whole axon depolarizes at the same time.
C) one action potential stimulates the production of a new action potential at the adjacent site.
D) an action potential is conducted from one node of Ranvier to the next node.

E) A) and B)
F) A) and D)

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Which of the following events is NOT a characteristic of an action potential?


A) The plasma membrane becomes highly permeable to sodium ions and depolarization results.
B) As sodium ions enter, the inside of the plasma membrane becomes more negative.
C) At the peak of depolarization, sodium channels begin to close and potassium channels open.
D) In repolarization, potassium ions flow out of the cell.
E) Action potentials occur according to the all-or-none principle.

F) B) and C)
G) A) and E)

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Action potentials are conducted more rapidly when transmission is


A) from node to node on a myelinated axon.
B) on a small diameter axon.
C) on an unmyelinated axon.
D) from internode to internode.
E) from internode to node on a myelinated axon.

F) None of the above
G) A) and B)

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A

Match the neuroglial cell with its function. -oligodendrocyte


A) influence function of blood-brain barrier
B) macrophages in CNS
C) produce cerebrospinal fluid
D) form myelin sheath around axons in CNS
E) form myelin sheath around part of the axon in the PNS

F) A) and E)
G) All of the above

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Suppose both excitatory and inhibitory neurons synapse with a single postsynaptic neuron. What determines if an action potential is initiated in the postsynaptic neuron?


A) the kind of neuron involved
B) the size of the neuron involved
C) whether the neuron is myelinated or non-myelinated
D) the number of EPSPs in relation to the number of IPSPs
E) This situation is not possible in humans.

F) C) and D)
G) None of the above

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Action potentials at a chemical synapse


A) travel from presynaptic terminal to postsynaptic membrane.
B) travel from postsynaptic membrane to presynaptic terminal.
C) travel back and forth from presynaptic terminal to postsynaptic membrane.
D) travel from presynaptic terminal to presynaptic membrane.
E) stop at the presynaptic terminal and are regenerated on the postsynaptic membrane.

F) C) and E)
G) B) and D)

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Damage to a postsynaptic membrane would


A) increase neurotransmitter release.
B) decrease the release of neurotransmitter.
C) increase neurotransmitter production.
D) interfere with the ability to respond to neurotransmitter.
E) destroy vesicles containing neurotransmitter.

F) A) and B)
G) B) and E)

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