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Which of the following is a febrile disease characterized by a rash and is caused by a virus that can cross the placenta to cause serious fetal damage?


A) Measles
B) Smallpox
C) Rubella
D) Shingles
E) Impetigo

F) B) and D)
G) All of the above

Correct Answer

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Oral lesions called Koplik's spots are seen in patients with ______.


A) measles
B) rubella
C) croup
D) influenza
E) mumps

F) B) and C)
G) A) and B)

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Cutaneous anthrax is _______.


A) seen in epidemic proportions in the United States
B) transmitted by contact
C) found only in humans
D) a high mortality disease

E) A) and C)
F) B) and D)

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Among the natural defenses present in tears is the protein lactoferrin. As you can infer from its name, it is also present in milk and other body secretions, and its function involves binding iron ions. The presence of lactoferrin in tears is protective against bacterial infection because _______.


A) all pathogens must acquire iron from their environment and lactoferrin ensures that the iron concentration is low
B) in the presence of lysozyme, as found in tears, the proteins form a protective barrier on the lens
C) pathogens with magnetosomes will be segregated from the eye tissue and swept away by the tears
D) free iron serves as an immune signal to recruit T cells to the eye

E) A) and D)
F) A) and B)

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Which of the following statement(s) is/are correct regarding fifth disease?


A) It is caused by Parvovirus B19.
B) It is a childhood febrile disease characterized by a red rash on the cheeks.
C) The causative agent is capable of crossing the placenta.
D) It is characterized by a maculopapular rash that lasts for days to weeks.
E) All of the choices are correct.

F) A) and B)
G) A) and C)

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The enzyme that clots plasma is ______.


A) hyaluronidase
B) catalase
C) kinase
D) staphylokinase
E) coagulase

F) A) and B)
G) C) and E)

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The integument includes all of the following except ______.


A) sweat glands
B) skin
C) nails
D) surface capillaries
E) hair

F) B) and C)
G) All of the above

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Which of the following is not true of cellulitis?


A) It causes pain, tenderness, swelling, and warmth.
B) It is caused by S. aureus or S. pyogenes.
C) It affects the epidermis layer of the skin.
D) Lymphangitis may occur with this infection.
E) Surgery may be required for treatment.

F) B) and D)
G) A) and C)

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Which of the following statements is correct regarding rubella?


A) It is not preventable by a vaccine.
B) It manifests as high fever, severe sore throat, severe cough, and myalgia.
C) It is associated with congenital transmission causing miscarriage, deafness, and cardiac and mental defects in the infant.
D) It is caused by the measles virus (Morbillivirus) .

E) A) and B)
F) None of the above

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Protective features of the skin include all of the following except ______.


A) resident biota
B) high pH
C) high salt content
D) a keratinized surface
E) lysozyme

F) D) and E)
G) A) and D)

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Measles is described as a ______ skin lesion.


A) macule
B) maculopapular
C) vesicular
D) pustular
E) bulla

F) None of the above
G) All of the above

Correct Answer

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Human herpesvirus 3 (HHV-3) _______.


A) uses the respiratory epithelium as its portal of entry
B) becomes latent in dorsal root ganglia that serve specific dermatomes
C) has humans as its reservoir
D) causes chickenpox and shingles
E) All of the choices are correct.

F) All of the above
G) C) and E)

Correct Answer

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Which of the following statements is incorrect regarding the effects of rubella and rubeola in different populations?


A) Congenital rubella is least serious if it is contracted during the final trimester of pregnancy.
B) A six-year-old child infected with rubeola will experience fever, cough, and a rash, and barring complications, should recover in a few weeks.
C) Infection during pregnancy with either of these viruses can cause serious injury to the fetus.
D) A 30-year-old man infected with rubella will experience severe symptoms and require constant medical attention for several weeks.

E) A) and B)
F) B) and D)

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What is the only way to prevent non-neonatal conjunctivitis?


A) Insect repellent
B) Screen pregnant women
C) Prophylactic antiviral chemotherapy
D) Good hygiene
E) Vaccine

F) A) and B)
G) A) and C)

Correct Answer

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Which of the following statements does not pertain to Streptococcus pyogenes?


A) It secretes streptokinase.
B) It coats itself with host proteins.
C) It causes impetigo.
D) It is often spread from an endogenous source.
E) It causes gas gangrene.

F) C) and D)
G) B) and E)

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The disease pathogenesis seen in river blindness is caused by ______.


A) Wolbachia bacteria
B) Onchocerca volvulus worms
C) a blood fluke
D) herpes simplex virus type 1 (HSV-1)
E) Both Wolbachia and Onchocerca volvulus are correct.

F) A) and E)
G) A) and D)

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Occassionally, Staphylococcus epidermidis may be isolated from the eye.

A) True
B) False

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Considering the diseases and conditions described in this chapter, those transmitted by respiratory droplets are caused by ______.


A) viruses
B) bacteria
C) fungi
D) All of these choices are correct.

E) B) and D)
F) None of the above

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Impetigo can be caused by either Staphylococcus aureus or Streptococcus pyogenes. Culture- based identification of the causative organism can be complicated by _______.


A) their common optimal growth temperature, 37°C
B) the fastidious nature of both organisms
C) the ability of S. aureus to kill S. pyogenes
D) the common surface antigens of these two organisms

E) A) and D)
F) A) and C)

Correct Answer

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Which material in skin provides protection from abrasions, water damage, and microorganism entry?


A) Keratin
B) Lysozyme
C) Sweat
D) Sebum
E) Salt

F) A) and E)
G) D) and E)

Correct Answer

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