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During DNA replication,the enzyme ________ catalyzes the elongation of new DNA strands.


A) helicase
B) DNA polymerase
C) DNA ligase
D) ATP synthase

E) A) and D)
F) A) and C)

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Codons


A) are each comprised of a triplet of nucleotides.
B) are unambiguous.
C) provide the instructions for synthesizing proteins.
D) All of the choices are correct.

E) A) and B)
F) A) and C)

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One of Chargaff's rules states that


A) A = T and G = C.
B) A = C and T = G.
C) A = G and T = C.
D) A = T + G + C.

E) All of the above
F) A) and C)

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If one strand of DNA has the base sequence AAG-CAA,the complementary strand has which of the following sequences?


A) UUC-GUU
B) TTC-GTT
C) AAG-CAA
D) UTC-GTU
E) TTC-GTG

F) B) and C)
G) B) and E)

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If a DNA sample contains 13% adenine,what percentage of the sample contains cytosine?


A) 13%
B) 37%
C) 26%
D) 74%

E) B) and C)
F) None of the above

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Which of the following statements is NOT true about the debate over the nature of genetic material?


A) Many scientists believed that DNA was not the genetic material because,with only four types of nucleotides,DNA did not have enough variability to store information.
B) Scientists focused on carbohydrate and protein in their studies of possible genetic material since they knew that genes were on chromosomes and that chromosomes were made of carbohydrate and protein.
C) Many scientists thought that proteins had a greater capacity for storing information because proteins contain 20 amino acids that could be sequenced differently.
D) Some scientists thought that RNA was likely to be the genetic material.

E) A) and C)
F) B) and C)

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Telomerase is an enzyme that unwinds DNA during DNA replication.

A) True
B) False

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Write an essay describing the 3 main steps of DNA replication in the correct order.Be sure to include the key structures involved in the process.

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Answers will vary but should include the...

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Which of the following statements applies to the semiconservative nature of DNA replication?


A) The old strands serve as a template for the new strand.
B) The old strand is pulled apart and reformed into the new strand.
C) The new strand serves as a template for the old strand.
D) None of these statements apply to the semiconservative nature of DNA replication.

E) B) and D)
F) C) and D)

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Which of the following statements about DNA replication is NOT correct?


A) Unwinding of the DNA molecule occurs as hydrogen bonds break.
B) Replication occurs as each base is paired with another exactly like it.
C) The process is known as semiconservative replication because one old strand is conserved in the new molecule.
D) The enzyme that catalyzes DNA replication is DNA polymerase.
E) Complementary base pairs are held together with hydrogen bonds.

F) A) and B)
G) None of the above

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Which of the following statements are true about DNA replication in eukaryotes? Select all that apply.


A) Replication of the entire genome takes about ten minutes.
B) A replication fork occurs at each growing point of the replicating chromosome(s) .
C) Eukaryotes have many different chromosomes,with replication occurring in each at the same time.
D) Replication occurs at the rate of about 500-5000 base pairs per minute.
E) Multiple sites of replication are present on each chromosome.

F) B) and D)
G) C) and D)

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An unknown chemical is analyzed and found to contain the bases thymine and guanine.This chemical is most likely


A) tRNA.
B) mRNA.
C) DNA.
D) rRNA.

E) All of the above
F) A) and D)

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Which of the following would be transcribed into mRNA?


A) a noncoding gene
B) a protein-coding gene
C) a promoter
D) a ribozyme

E) A) and B)
F) A) and C)

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A sample of Chargaff's data on the DNA base composition in various species is provided.Discuss several conclusions that may be drawn from this data.  SPECIES  A TGC Hurnar1 31.031.519.418.4 Fruit fly 27.327.622.522.5 Corn 25.625.324.524.6 Neurospora (furgus) 23.023.327.126.6 E coli (bacteriurn) 24.624.325.525.6\begin{array} { | c | c | c | c | c | } \hline \text { SPECIES } & \text { A } & \mathrm { T } & \mathrm { G } & \mathrm { C } \\\hline \text { Hurnar1 } & 31.0 & 31.5 & 19.4 & 18.4 \\\hline \text { Fruit fly } & 27.3 & 27.6 & 22.5 & 22.5 \\\hline \text { Corn } & 25.6 & 25.3 & 24.5 & 24.6 \\\hline \text { Neurospora (furgus) } & 23.0 & 23.3 & 27.1 & 26.6 \\\hline \text { E coli (bacteriurn) } & 24.6 & 24.3 & 25.5 & 25.6 \\\hline\end{array}

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Answers may vary.Several conclusions may...

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DNA replication is considered semiconservative because


A) it will create three new identical strands when finished.
B) it uses one old strand as a template for the synthesis of a new strand.
C) it always replicates in the 3' to 5' prime direction.
D) it never replicates in the 5' to 3' prime direction.

E) A) and B)
F) B) and D)

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Which of the following amino acid chains would be produced from the mRNA sequence AUA-CUU-CCU-AGU-UGA?


A) Isoleucine - leucine - proline - serine - stop
B) Isoleucine - leucine - stop - proline - serine
C) Glycine - glutamate - lysine - lysine - stop
D) Isoleucine - alanine - proline - serine - stop

E) A) and D)
F) None of the above

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Determine the number of codon sequences it would require to produce the following amino acid sequence: alanine - proline - serine - isoleucine - stop.


A) It would take 5 codon sequences.
B) It would take 3 codon sequences.
C) It would take 6 codon sequences.
D) It would take 4 codon sequences.

E) None of the above
F) B) and C)

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Approximately how many base pairs are improperly matched before being repaired by the DNA polymerase?


A) 1 in 10,000
B) 1 in 100,000
C) 1 in 1,000,000
D) 1 in 10,000,000
E) 1 in a billion

F) B) and E)
G) B) and D)

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Which statement is NOT true about DNA replication in prokaryotes?


A) Replication begins at a single origin of replication.
B) Replication is bidirectional from the origin(s) .
C) Replication occurs at about 1 million base pairs per minute.
D) Since bacterial cells replicate so rapidly,a second round of replication may begin before the first has been completed.
E) There are many bacterial chromosomes,with replication occurring in each at the same time.

F) B) and E)
G) C) and D)

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In order to help firmly establish DNA as the genetic material,Hershey and Chase radioactively tagged viral protein in one experiment and radioactively tagged viral RNA in the other experiment.

A) True
B) False

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