Question 1

Drug susceptibility testing

Accepted Answer

A)   determines the patient's response to various antimicrobics.
B)   determines the pathogen's response to various antimicrobics.
C)   determines if normal flora will be affected by antimicrobics.
D)   determines if the drug is increasing to toxic levels in a patient.
E)   determines the pathogen's identity.F) B) and D)
G) B) and C)

Question 2

Which organ is responsible for metabolizing and detoxifying foreign chemicals in the blood, including drugs?

Accepted Answer

A)   liver
B)   kidneys
C)   gallbladder
D)   spleen
E)   stomachF) A) and B)
G) A) and E)

Question 3

Polyene drugs bind to fungal _____ and cause loss of selective permeability.

Accepted Answer

cell membr...

Question 4

Which of the following is not a mode of action of an antiviral?

Accepted Answer

A)   Block viral entry into a host cell
B)   Block transcription and translation
C)   Inhibit DNA synthesis
D)   Block maturation
E)   Bond to ergosterol in the cell membraneF) C) and D)
G) B) and D)

Question 5

Which of the following will influence a physician's decision to prescribe an antimicrobial?

Accepted Answer

A)   patient age
B)   pregnancy
C)   liver function
D)   alcohol use
E)   All of these choices are correct.F) All of the above
G) A) and B)

Question 6

An antiviral that is a guanine analog would have an antiviral mode of action that

Accepted Answer

A)   blocks penetration.
B)   blocks DNA replication.
C)   inhibits peptidoglycan cross-linking.
D)   blocks maturation.
E)   bonds to ergosterol in the cell membrane.F) C) and D)
G) A) and E)

Question 7

Antibiotics are derived from all the following except

Accepted Answer

A)   Penicillium.
B)   Bacillus.
C)   Staphylococcus.
D)   Streptomyces.
E)   Cephalosporium.F) All of the above
G) None of the above

Question 8

One of the greatest challenges in development of antivirals is finding drugs that are

Accepted Answer

A)   administered orally.
B)   absorbed by the GI tract.
C)   not likely to disrupt the normal microbiota of the patient.
D)   selectively toxic for viruses.E) A) and B)
F) C) and D)

Question 9

If pathogen A is more resistant to an erythromycin disc on a Kirby-Bauer plate compared to pathogen B, then pathogen A will have a _____ zone of inhibition compared to pathogen
B.

Accepted Answer

The answer of If pathogen A is more resistant to...

Question 10

The Kirby-Bauer test uses an agar surface, seeded with the test bacterium, to which small discs containing a specific concentration of several drugs are placed on the surface.

Accepted Answer

A) True 
 B)False

Question 11

Discuss 5 factors that have influenced the increasing development of resistant microbial strains.

Accepted Answer

1. Overuse and misuse of antibiotics: Th...

Question 12

A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions. This is called the

Accepted Answer

A)   Kirby-Bauer technique.
B)   antibiogram.
C)   E-test.
D)   minimum inhibitory concentration MI
C)  .
E)   therapeutic index TI) .F) B) and E)
G) B) and C)

Question 13

Nutrients that encourage the growth of beneficial microbes in the intestines are called ________.

Accepted Answer

The answer of Nutrients that encourage the growth of beneficial...

Question 14

The development of successful antiviral drugs has been relatively easy because viral structure is so different from the structure of eukaryotic cells.

Accepted Answer

A) True 
 B)False

Question 15

Antimicrobics effective against a wide variety of microbial types are termed

Accepted Answer

A)   antibiotics.
B)   narrow-spectrum drugs.
C)   semisynthetic drugs.
D)   synthetic drugs.
E)   broad-spectrum drugs.F) B) and C)
G) A) and B)

Question 16

A chemical that inhibits beta-lactamase enzymes is

Accepted Answer

A)   synercid.
B)   penicillinase.
C)   aztreonam.
D)   clavulanic acid.
E)   imipenem.F) C) and E)
G) D) and E)

Question 17

An antimicrobic with a low therapeutic index is a safer choice compared to a drug with a high therapeutic index.

Accepted Answer

A) True 
 B)False

Question 18

Acyclovir is used to treat

Accepted Answer

A)   influenza A virus.
B)   HIV.
C)   shingles, chickenpox, and genital herpes.
D)   respiratory syncytial virus.
E)   hepatitis C virus.F) B) and C)
G) B) and D)

Question 19

A semisynthetic antibiotic is a drug which is chemically modified in the laboratory after being isolated from natural sources.

Accepted Answer

A) True 
 B)False

Question 20

Discuss the problems with development of antifungal, antiprotozoan, antihelminth, and antiviral drugs compared to the antibacterial drugs. Discuss at least 3 different modes of action that have been developed for these drugs.

Accepted Answer

The development of antifungal, antiproto...

Exam 12: Drugs, Microbes, Host--The Elements of Chemotherapy

Nutrients that encourage the growth of beneficial microbes in the intestines are called ________.

Correct AnswerverifiedShow Answer

A chemical that inhibits beta-lactamase enzymes is

Correct AnswerverifiedShow Answer

Which of the following is not a mode of action of an antiviral?

Correct AnswerverifiedShow Answer

The development of successful antiviral drugs has been relatively easy because viral structure is so different from the structure of eukaryotic cells.

Correct AnswerverifiedShow Answer

If pathogen A is more resistant to an erythromycin disc on a Kirby-Bauer plate compared to pathogen B, then pathogen A will have a _____ zone of inhibition compared to pathogen B.

Correct AnswerverifiedShow Answer

A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions. This is called the

Correct AnswerverifiedShow Answer

An antimicrobic with a low therapeutic index is a safer choice compared to a drug with a high therapeutic index.

Correct AnswerverifiedShow Answer

Antimicrobics effective against a wide variety of microbial types are termed

Correct AnswerverifiedShow Answer

Polyene drugs bind to fungal _____ and cause loss of selective permeability.

Correct Answerverifiedcell membr...View AnswerShow Answer

Discuss 5 factors that have influenced the increasing development of resistant microbial strains.

Correct AnswerAnswered by ExamLex AI1. Overuse and misuse of antibiotics: Th...View AnswerShow Answer

Which of the following will influence a physician's decision to prescribe an antimicrobial?

Correct AnswerverifiedShow Answer

One of the greatest challenges in development of antivirals is finding drugs that are

Correct AnswerverifiedShow Answer

Drug susceptibility testing

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Discuss the problems with development of antifungal, antiprotozoan, antihelminth, and antiviral drugs compared to the antibacterial drugs. Discuss at least 3 different modes of action that have been developed for these drugs.

Correct AnswerAnswered by ExamLex AIThe development of antifungal, antiproto...View AnswerShow Answer

Antibiotics are derived from all the following except

Correct AnswerverifiedShow Answer

Acyclovir is used to treat

Correct AnswerverifiedShow Answer

The Kirby-Bauer test uses an agar surface, seeded with the test bacterium, to which small discs containing a specific concentration of several drugs are placed on the surface.

Correct AnswerverifiedShow Answer

An antiviral that is a guanine analog would have an antiviral mode of action that

Correct AnswerverifiedShow Answer

A semisynthetic antibiotic is a drug which is chemically modified in the laboratory after being isolated from natural sources.

Correct AnswerverifiedShow Answer

Which organ is responsible for metabolizing and detoxifying foreign chemicals in the blood, including drugs?

Correct AnswerverifiedShow Answer

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cell membr...
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1. Overuse and misuse of antibiotics: Th...
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Answered by ExamLex AI
The development of antifungal, antiproto...
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